Chemical profile of wild salvia officinalis population from Kosovo by using CO2 supercritical extraction

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Miranda Misini
Arben Haziri
Fatmir Faiku
Aurel Nuro


This study shows chemical profile of Salvia officinalis L. plants by using CO2 supercritical extraction method. Samples of sage plants were selected by natural population of Gjilan, Kosovo. Sage samples were obtained in August 2022. The dried and ground plants were subjected of CO2 supercritical extraction techniques in a modified Clevenger apparatus, to obtain the essential oil of Salvia officinalis plants. Chemical profiles for all sage samples were performed using the GC/FID technique. Capillary column VF-1ms (30 m x 0.33 mm x 0.25 um) was used for the separation and isolation of compounds found in sage plants. In the analyzed chromatograms from sage samples, 30-45 compounds were identified. In the study, the 20 main compounds that make up over 90% of the total identified compounds were considered. Oxygenated monoterpenes were the main group of monoterpenes because of higher values for alpha + beta-Thujones and Camphor.  Sesquiterpenes were the second group while bicyclic monoterpenes were third group of terpenes.  Percentages of monocyclic, aliphatic and aromatic monoterpenes were found in non-considerable level. Chemical profile of Salvia officinalis plants from Kosovo was the same with other reported studies from Balkan and Mediterranean area.

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Misini, M., Haziri, A., Faiku, F. ., & Nuro, A. (2024). Chemical profile of wild salvia officinalis population from Kosovo by using CO2 supercritical extraction. Engineering Applications, 3(1), 78–84. Retrieved from


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