The effect of microbiota in mood disorders: Utilization of probiotics as a therapeutical approach

Authors

  • Hazal Altundağ
  • Furkan Ayaz

Keywords:

Anxiety, Gut microbiota, Probiotic, Microorganism

Abstract

There are trillions of microorganisms in the human body. All microbial communities in the gastrointestinal tract are intestinal microbiota. The main task of this community can be counted as; defense against diseases, digestion of food, etc. Moreover, they have effect on the human mood and behaviors. In addition to its basic functions, the brain-gut relationship, which has been the subject of many studies recently, draws attention.  Based on this relationship, it is noteworthy that the microbiota disorder causes anxiety and depression, and the use of probiotics seems as a promising solution. In this proceeding review, we will be discussing this theme more in depth.

References

Laursen, M. F. (2021). Gut microbiota development: influence of diet from infancy to toddlerhood. Annals of Nutrition and Metabolism, 77(3), 21-34.

Milani, C., Duranti, S., Bottacini, F., Casey, E., Turroni, F., Mahony, J., ... & Ventura, M. (2017). The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota. Microbiology and molecular biology reviews, 81(4), https://doi.org/10.1128/mmbr.00036-17

Kalip, K., & Atak, N. (2018). Bağırsak mikrobiyotası ve sağlık. Turkish Journal of Public Health, 16(1), 58-73.

Yoo, B. B., & Mazmanian, S. K. (2017). The enteric network: interactions between the immune and nervous systems of the gut. Immunity, 46(6), 910-926.

Wang, H. X., & Wang, Y. P. (2016). Gut microbiota-brain axis. Chinese medical journal, 129(19), 2373-2380.

Bravo, J. A., Forsythe, P., Chew, M. V., Escaravage, E., Savignac, H. M., Dinan, T. G., ... & Cryan, J. F. (2011). Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve. Proceedings of the National Academy of Sciences, 108(38), 16050-16055.

Bear, T. L., Dalziel, J. E., Coad, J., Roy, N. C., Butts, C. A., & Gopal, P. K. (2020). The role of the gut microbiota in dietary interventions for depression and anxiety. Advances in Nutrition, 11(4), 890-907.

Zendeboodi, F., Khorshidian, N., Mortazavian, A. M., & da Cruz, A. G. (2020). Probiotic: conceptualization from a new approach. Current Opinion in Food Science, 32, 103-123.

Uymaz, B. (2010). Probiyotikler ve Kullanım Alanları. Pamukkale Üniversitesi Mühendislik Bilimleri Dergisi, 16(1), 95-104

do Nascimento, A. S. M., & da AnunciaÃ, T. A. (2020). Psychobiotics in daily food against psychiatric disorders. African Journal of Food Science, 14(6), 161-166.

Luo, J., Wang, T., Liang, S., Hu, X., Li, W., & Jin, F. (2014). Ingestion of Lactobacillus strain reduces anxiety and improves cognitive function in the hyperammonemia rat. Science China Life Sciences, 57, 327-335.

Messaoudi, M., Lalonde, R., Violle, N., Javelot, H., Desor, D., Nejdi, A., ... & Cazaubiel, J. M. (2011). Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. British Journal of Nutrition, 105(5), 755-764.

Downloads

Published

2023-07-30