Different types, pathogenesis and cytokine network of Psoriasis
Keywords:
Psoriasis, Cytokine, Keratinocyte cells, HyperproliferationAbstract
Psoriasis is an autoimmune and dermatological disease characterized by high differentiation of keratinocyte cells, which are found in 5% of the skin. In the pathogenesis of psoriasis, functional changes in the HLA-Cw susceptibility allele and dendritic cells, which play an important role in cytokine secretion, helper T cells and keratinocytes are involved. With the alteration of this susceptibility allele, psoriasis is categorized in 7 different phenotypes, according to the sites of involvement. The treatment of the disease is possible in different ways such as topical, systemic and phototherapy. In this review proceeding, we will focus on different types and pathogenesis of psoriasis.
References
Weigle, N., & McBane, S. (2013). Psoriasis. American family physician, 87(9), 626.
Luba, K. M., & Stulberg, D. L. (2006). Chronic plaque psoriasis. South African Family Practice, 48(9), 20-29.
Syed, Z. U., & Khachemoune, A. (2011). Inverse psoriasis: case presentation and review. American journal of clinical dermatology, 12, 143-146.
Chalmers, R. J. G., O'sullivan, T., Owen, C. M., & Griffiths, C. E. M. (2001). A systematic review of treatments for guttate psoriasis. British Journal of Dermatology, 145(6), 891-894.
Rosenbach, M., Hsu, S., Korman, N. J., Lebwohl, M. G., Young, M., Bebo Jr, B. F., & Van Voorhees, A. S. (2010). Treatment of erythrodermic psoriasis: from the medical board of the National Psoriasis Foundation. Journal of the American Academy of Dermatology, 62(4), 655-662.
Robinson, A., Van Voorhees, A. S., Hsu, S., Korman, N. J., Lebwohl, M. G., Bebo Jr, B. F., & Kalb, R. E. (2012). Treatment of pustular psoriasis: from the Medical Board of the National Psoriasis Foundation. Journal of the American Academy of Dermatology, 67(2), 279-288.
Reich, K. (2009). Approach to managing patients with nail psoriasis. Journal of the European Academy of Dermatology and Venereology, 23, 15-21.
Ritchlin, C. T., Colbert, R. A., & Gladman, D. D. (2017). Psoriatic arthritis. New England Journal of Medicine, 376(10), 957-970.
Naldi, L. (2004). Epidemiology of psoriasis. Current Drug Targets-Inflammation & Allergy, 3(2), 121-128.
Baliwag, J., Barnes, D. H., & Johnston, A. (2015). Cytokines in psoriasis. Cytokine, 73(2), 342-350.
