RNA-Based therapeutic oligonucleotide strategies

Abstract

Oligonucleotides, which have RNA-based therapeutic effects, constitute therapeutic strategies with very high potential with the elucidation of the mechanism of action of RNA molecules in cellular processes and with the developing technology. These strategies offer new alternatives for the mechanisms, pathophysiological processes, diagnosis, treatment, and prevention of many diseases. It also opens new doors to many pathophysiological pathways previously known as "non-targetable". RNA-based oligonucleotides are promising new therapeutic modalities thanks to the diverse reservoir of molecular tools they provide.