The role of Notch and Wnt signaling pathways in neurodevelopment
Keywords:
Signaling pathway, Neuron, Neurodevelopment, Diseases, CancerAbstract
Notch is a protein that decides the path that cells should take by interacting with its ligands. The Notch signaling pathway is involved in performing functions that ensure cell survival.Notch activity mediates the formation of new structures from certain cells with its effect on differentiation, proliferation and apoptosis of cell. Similarly, Wnt signaling pathway sare involved in versatile signal transduction pathways that start with proteins that transmit signals to a cell via cell surface receptors and have many functions, including the control of neurogenesis. In this review proceeding, we will address the role of Notch and Wnt signaling pathways on neuronal development.
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